Antivegf Injections

How does an anti - VEGF injection prevent sight loss?

Anti - VEGF medicines stop the abnormal blood vessels growing, then leaking and bleeding under the retina. This prevents or limits damage to the retinal light receptors and loss of central vision. These medicines are effective in preventing further central vision loss in up to

90% of treated eyes.

Is anti - VEGF treatment right for me?

Your ophthalmologist will advise if the treatment is appropriate for you and which anti - VEGF medicine will be used. Only patients with active leaking of blood and fluid can benefit

from it. The treatment that’s right for you will depend on the specific condition of your central retina (macula), your vision and whether there is scarring at the macula. We perform scans and photographs of the eye which show us the different layers of the retina. These scans can show us if there is blood or fluid present within the retinal layers and help us decide on your treatment.

How is the treatment given?

The drug is injected into your eye with a fine needle. Minimal discomfort is to be expected (equivalent to having blood taken from your arm). The procedure takes five to seven

minutes, but the injection itself is over in less than 20 seconds.

The injection is given with you lying down comfortably on the couch. Firstly, local anesthetic drops are applied to numb your eye and minimize discomfort. Then, your eyelids and surface of the eye are cleaned to prevent infection. Your ace and the area around your eye will be covered by a small surgical sheet (a drape) to keep the area sterile. A small clip (speculum) will be used to keep the eye open. The injection site is marked with calipers and your eye is stabilized with forceps or a cotton bud. A few seconds later, the injection is given. The injecting clinician will use lubricating drops after your injection. Your vision is assessed post injection by checking you can see hand movements or can count fingers.

What are the risks with these injections?

As with any medical procedure, there is a small risk of complications following anti-VEGF treatment. Most complications that might occur are from the injection itself, rather than the drug.

For most patients, the benefit of the treatment outweighs the small risk of injection injury.

The following are some of the major potential risks and side effects of anti-VEGF injections.

It is important to note that these risks are all rare and significant loss of vision due to this treatment is very uncommon. Some common side effects that could occur include:

• Red eye (there is usually a bleed or bruise on the white part of the eye at the site of injection, which clears in a week or two).
• Sore and gritty eye (slight ache and discomfort lasting a day or two).
• ‘Blobs’ or ‘small specks’ in your vision (‘floaters’) might be seen for a few days after the injection. You may also experience transient flashing lights or swirls of light immediately after the injection.

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